1H-Pyrazole-3-carboxylicacid 5-methyl-(CAS# 696-22-0)
| Matšoao a Kotsi | Xi - Ea halefisang |
| Likhoutu tsa Kotsi | R36/37/38 – Ho tena mahlo, tsamaiso ya ho hema le letlalo. |
| Tlhaloso ea Tšireletseho | S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka. S37/39 - Apara liatlana tse loketseng le tšireletso ea mahlo / sefahleho |
Selelekela
Ke motsoako oa manyolo o nang le foromo ea lik'hemik'hale C5H5N2O2. Ha e le hantle, ha e na 'mala ho isa ho 'mala o mosehla o tiileng oa kristale.
Motsoako o na le lihlopha tse peli tse sebetsang, e 'ngoe ke selikalikoe sa pyrazole' me e 'ngoe ke sehlopha se sebetsang sa carboxylic acid. E na le ho qhibiliha ho itekanetseng 'me e qhibiliha ka metsing le ka har'a metsoako e tloaelehileng ea tlhaho. Sehlopha sa methyl sebopeho sa eona se etsa hore e be hydrophobic.
Joaloka motsoako oa heterocyclic, 5-methyl-e na le mefuta e sa tšoaneng ea mesebetsi ea likokoana-hloko. E sebelisoa haholo lipatlisisong tsa meriana le motsoako oa lithethefatsi, hangata e le thepa e tala kapa e bohareng. Lisebelisoa tse khethehileng li kenyelletsa motsoako oa li-analogue tsa vithamine B1, likokoanyana tse bolaeang likokoanyana, li-plavix inhibitors (motsoako o sebelisetsoang ho thibela kholo ea limela), joalo-joalo.
Tokisetso, 5-methyl-e ka fumanoa ka ho arabela athomo ea nitrogen ea reng ea pyrazole ka methylating agent (mohlala, methyl iodide). Mokhoa ona o etsoa ke karabelo ea N-methylation, mokhoa o tloaelehileng ke karabelo ea nucleophile e tsamaisanang le N-methyl reagent.
