1-Phenyl-3,4-dihydroisoquinoline(CAS#52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline(CAS#52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline, nomoro ea CAS 52250-50-7, e bontšitse khahleho e ikhethang tšimong ea k'hemistri le meriana.
Ho tloha ho lik'hemik'hale tsa lik'hemik'hale, molek'hule ea eona e kopantsoe ka bohlale le lihlopha tsa moralo tse kang sehlopha sa phenyl le lesale la dihydroisoquinoline, 'me mokhoa ona o khethehileng oa khokahanyo ea athomo o haha kabo e ikhethang ea leru la elektronike, e leng se etsang hore lik'hemik'hale tsa eona tse khethehileng le botsitso. Ka ponahalo, hangata e hlahisoa e le e tiileng e nang le mofuta o itseng oa kristale, 'mala o na le boholo bo tšoeu kapa bo bosoeu,' me mohaho oa kristale o tloaelehile ebile o hlophisehile, o loketseng ho hloekisoa le ho hloekisa ka mokhoa oa ho tsosolosa. Mabapi le solubility, e bontša mokhoa o itseng oa ho qhibiliha ka har'a metsoako e tloaelehileng ea lintho tse phelang tse kang ethanol le acetone, empa ho qhibiliha ha metsi ho batla ho le tlaase, e amanang haufi-ufi le polarity ea molek'hule, hape e fana ka motheo oa ho khetha mekhoa ea solvent bakeng sa karohano e latelang le karabelo ea motsoako.
Mabapi le menyetla ea R&D ea meriana, e na le ts'ebetso e ka bang teng ea baeloji. Sebopeho sa lik'hemik'hale sa sehlahisoa se tšoana le sa lihlahisoa tse ling tsa tlhaho tse sebetsang ka meriana, ho fana ka maikutlo a hore e ka 'na ea e-ba le lipakane tse tšoanang. Patlisiso ea pele e fana ka maikutlo a hore e kanna ea ba le tšusumetso litseleng tsa matšoao a methapo ea kutlo, 'me e lebelletsoe ho kenya letsoho ntlafatsong ea litlhare tse ncha tsa mafu a neurodegenerative, joalo ka lefu la Alzheimer le lefu la Parkinson, ka ho laola phetiso e sa tloaelehang ea li-neurotransmitter le ho thibela hyperapoptosis ea lisele tsa methapo. Ka nako e ts'oanang, tšimong ea anti-tumor, lihlopha tse sebetsang ka sebopeho sa eona li ka kena-kenana le ts'ebetso ea ho ata, ho falla le ho hlasela ha lisele tsa hlahala, ho bula maikutlo a macha bakeng sa phekolo ea kankere, ha e le hantle, tsena li ntse li le mathoasong. sethaleng sa lipatlisiso tsa laboratori, 'me ho ntse ho e-na le mosebetsi o mongata oa lipatlisiso o lokelang ho etsoa pele ho kopo ea tleliniki.
Ho latela pono ea liindasteri, mokhoa oa hajoale oa motsoako oa lik'hemik'hale o ts'eptjoa haholo, ho qala ka lisebelisoa tse tala, ka karabelo ea mehato e mengata ho aha skeleton e rarahaneng ea limolek'hule, ts'ebetso e kenyelletsa cyclization, substitution, condensation le mefuta e meng ea khale ea karabelo ea manyolo. , bafuputsi ba tsoela pele ho ntlafatsa maemo a karabelo, ho ntlafatsa chai, ho fokotsa litšenyehelo, ho finyella litlhoko tsa ho latela lipatlisiso tse tebileng le ho khoneha ka tekanyo e kholo. tlhahiso. Ka ho kopanngoa ha thekenoloji likarolong tse fapa-fapaneng, tsoelo-pele e pota-potileng ea 1-Phenyl-3,4-dihydroisoquinoline e lebeletsoe ho potlakisa, ho kenya ts'ebetsong e ncha bophelong ba batho le tsoelo-pele ea saense le thekenoloji.
