1-Benzyl-1-phenylhydrazine (CAS# 614-31-3)
Kopo
E sebelisoa e le li-intermediate tsa meriana.
Tlhaloso
Ponahalo e metsi a hlakileng.
Mmala o mosehla o kganyang ho ya ho Brown.
pKa 5.21±0.10(E boletsoeng esale pele).
Refractive Index 1.6180-1.6210.
Polokeho
Risk Codes R20/21/22 - E kotsi ka ho hema, ka ho kopana le letlalo le haeba e koetsoe.
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36/37/39 - Apara liaparo tse loketseng tse sireletsang, liatlana le tšireletso ea mahlo / sefahleho.
Kotsi Class TSOHLE.
Ho paka & Polokelo
E pakiloeng ka meqomong ea 25kg/50kg. Maemo a Polokelo a Tiisitsoeng ka omileng, Mocheso oa Kamore.
Selelekela
Ha lefats'e la bongaka le ntse le tsoela pele ho fetoha, tlhokahalo ea li-intermediate tsa boleng bo holimo ha e so ka e ba kholo ho feta. E 'ngoe ea lipakeng tse joalo e fumaneng tlhokomelo e kholo lilemong tsa morao tjena ke 1-Benzyl-1-phenylhydrazine. Motsoako ona o nang le mefuta e mengata o na le mefuta e mengata ea lisebelisoa 'me o sebelisoa haholo ha ho etsoa lithethefatsi tse fapa-fapaneng le lihlahisoa tsa meriana. Sengoliloeng sena, re tla kenella ka botebo lefats'eng la 1-Benzyl-1-phenylhydrazine mme re hlahlobe thepa le ts'ebeliso ea eona e fapaneng.
1-Benzyl-1-phenylhydrazine ke mokelikeli o hlakileng o ka tlohang ka 'mala ho tloha mosehla o khanyang ho ea ho sootho. E na le boima ba molek'hule ea 211.28 le foromo ea molek'hule ea C14H14N2. Motsoako ona o qhibiliha haholo linthong tse fapaneng tse hlapollang tse kang acetone, chloroform le ethanol. E boetse e qhibiliha habonolo metsing 'me e ka kenngoa habonolo mefuteng e fapaneng ea lithethefatsi.
Lisebelisoa:
1-Benzyl-1-phenylhydrazine e na le mefuta e mengata ea likopo ho indasteri ea meriana. Ke karolo ea bohlokoa ea lipakeng tse sebelisoang ha ho etsoa litlhare tse 'maloa tse kang li-antidepressants, li-anti-inflammatory agents le litlhare tsa antihypertensive. Motsoako ona o boetse o sebelisoa ha ho etsoa litlhare tse fapaneng tsa mofetše le li-antiviral agents. Ho feto-fetoha ha 1-Benzyl-1-phenylhydrazine ho etsa hore e be karolo ea bohlokoa ho thehoeng ha lihlahisoa tse ngata tsa meriana.
Mekhatlo ea Meriana:
Li-intermediate tsa meriana ke metsoako e sebelisoang ha ho etsoa metsoako e fapaneng ea metsoako e sebetsang ea meriana (APIs). Li-intermediate tsena ke likarolo tsa bohlokoa tlhahisong ea lithethefatsi 'me li sebelisoa haholo ho theheng lihlahisoa tsa meriana. 1-Benzyl-1-phenylhydrazine ke e 'ngoe e joalo ea mahareng e bapalang karolo ea bohlokoa ho thehoeng ha lithethefatsi tse fapaneng. Lintho tsa eona tse nang le mesebetsi e mengata li etsa hore e be motsoako oa bohlokoa lefats'eng la meriana.
Boleng:
Boleng ba li-intermediate tsa meriana ke ba bohlokoa ka ho fetisisa ha ho tluoa tabeng ea ho etsa lithethefatsi tse sireletsehileng le tse sebetsang hantle. 1-Benzyl-1-phenylhydrazine ke motsoako o entsoeng tlas'a mehato e thata ea ho laola boleng ho netefatsa hore e finyella litekanyetso tse phahameng ka ho fetisisa tsa indasteri. Sena se tiisa hore litlhare tse entsoeng ka motsoako ona ke tsa boleng bo holimo 'me li bolokehile hore li ka sebelisoa ke bakuli.
Qetellong, 1-Benzyl-1-phenylhydrazine ke motsoako o nang le mekhoa e mengata e nang le lisebelisoa tse ngata indastering ea meriana. Bokhoni ba eona ba ho sebetsa e le setsi sa mesebetsi e mengata se etsa hore e be karolo ea bohlokoa ho etsoa ha lithethefatsi tse fapa-fapaneng le lihlahisoa tsa meriana. Mehato e tiileng ea taolo ea boleng e sebelisoang ha e etsoa e netefatsa hore meriana e entsoeng ka motsoako ona ke ea boleng bo phahameng ka ho fetisisa 'me e bolokehile hore e ka sebelisoa ke bakuli. Ha tlhokahalo ea lihlahisoa tsa meriana ea boleng bo phahameng e ntse e eketseha, metsoako e kang 1-Benzyl-1-phenylhydrazine e tla tsoela pele ho phetha karolo ea bohlokoa indastering ea meriana.
