1-Benzyl-1-phenylhydrazine (CAS# 614-31-3)
Kopo
E sebelisoa e le li-intermediate tsa meriana.
Tlhaloso
Ponahalo e metsi a hlakileng.
Mmala o mosehla o kganyang ho ya ho Brown.
pKa 5.21±0.10(E boletsoeng esale pele).
Refractive Index 1.6180-1.6210.
Polokeho
Risk Codes R20/21/22 - E kotsi ka ho hema, ka ho kopana le letlalo le haeba e koetsoe.
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
Tlhaloso ea Tšireletseho S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36/37/39 - Apara liaparo tse loketseng tse sireletsang, liatlana le tšireletso ea mahlo / sefahleho.
Kotsi Class TSOHLE.
Ho paka & Polokelo
E pakiloeng ka meqomong ea 25kg/50kg. Maemo a Polokelo a Tiisitsoeng ka omileng, Mocheso oa Kamore.
Selelekela
Ha lefats'e la bongaka le ntse le tsoela pele ho fetoha, tlhokahalo ea li-intermediate tsa boleng bo holimo ha e so ka e ba kholo ho feta. E 'ngoe ea lipakeng tse joalo e fumaneng tlhokomelo e kholo lilemong tsa morao tjena ke 1-Benzyl-1-phenylhydrazine. Motsoako ona o nang le mefuta e mengata o na le mefuta e mengata ea lisebelisoa 'me o sebelisoa haholo ha ho etsoa lithethefatsi tse fapa-fapaneng le lihlahisoa tsa meriana. Sengoliloeng sena, re tla kenella ka botebo lefats'eng la 1-Benzyl-1-phenylhydrazine mme re hlahlobe thepa le ts'ebeliso ea eona e fapaneng.
1-Benzyl-1-phenylhydrazine ke mokelikeli o hlakileng o ka tlohang ka 'mala ho tloha mosehla o khanyang ho ea ho sootho. E na le boima ba molek'hule ea 211.28 le foromo ea molek'hule ea C14H14N2. Motsoako ona o qhibiliha haholo linthong tse fapaneng tse hlapollang tse kang acetone, chloroform le ethanol. E boetse e qhibiliha habonolo metsing 'me e ka kenngoa habonolo mefuteng e fapaneng ea lithethefatsi.
Lisebelisoa:
1-Benzyl-1-phenylhydrazine e na le mefuta e mengata ea likopo ho indasteri ea meriana. Ke karolo ea bohlokoa ea lipakeng tse sebelisoang ha ho etsoa litlhare tse 'maloa tse kang li-antidepressants, li-anti-inflammatory agents le litlhare tsa antihypertensive. Motsoako ona o boetse o sebelisoa ha ho etsoa litlhare tse fapaneng tsa mofetše le li-antiviral agents. Ho feto-fetoha ha 1-Benzyl-1-phenylhydrazine ho etsa hore e be karolo ea bohlokoa ho thehoeng ha lihlahisoa tse ngata tsa meriana.
Mekhatlo ea Meriana:
Li-intermediate tsa meriana ke metsoako e sebelisoang ha ho etsoa metsoako e fapaneng ea metsoako e sebetsang ea meriana (APIs). Li-intermediate tsena ke likarolo tsa bohlokoa tlhahisong ea lithethefatsi 'me li sebelisoa haholo ho theheng lihlahisoa tsa meriana. 1-Benzyl-1-phenylhydrazine ke e 'ngoe e joalo ea mahareng e bapalang karolo ea bohlokoa ho thehoeng ha lithethefatsi tse fapaneng. Lintho tsa eona tse nang le mesebetsi e mengata li etsa hore e be motsoako oa bohlokoa lefats'eng la meriana.
Boleng:
Boleng ba li-intermediate tsa meriana ke ba bohlokoa ka ho fetisisa ha ho tluoa tabeng ea ho etsa lithethefatsi tse sireletsehileng le tse sebetsang hantle. 1-Benzyl-1-phenylhydrazine ke motsoako o entsoeng tlas'a mehato e thata ea ho laola boleng ho netefatsa hore e finyella litekanyetso tse phahameng ka ho fetisisa tsa indasteri. Sena se tiisa hore meriana e entsoeng ka motsoako ona ke ea boleng bo holimo 'me e bolokehile hore e ka sebelisoa ke bakuli.
Qetellong, 1-Benzyl-1-phenylhydrazine ke motsoako o nang le mekhoa e mengata e nang le lisebelisoa tse ngata indastering ea meriana. Bokhoni ba eona ba ho sebetsa e le setsi sa mesebetsi e mengata se etsa hore e be karolo ea bohlokoa ho etsoa ha lithethefatsi tse fapa-fapaneng le lihlahisoa tsa meriana. Mehato e tiileng ea taolo ea boleng e sebelisoang ha e etsoa e netefatsa hore meriana e entsoeng ka motsoako ona ke ea boleng bo phahameng ka ho fetisisa 'me e bolokehile hore e ka sebelisoa ke bakuli. Ha tlhokahalo ea lihlahisoa tsa meriana ea boleng bo phahameng e ntse e eketseha, metsoako e kang 1-Benzyl-1-phenylhydrazine e tla tsoela pele ho phetha karolo ea bohlokoa indastering ea meriana.
