β-thujaplicin (CAS# 499-44-5)

Thepa ea Lik'hemik'hale:

Foromo ea limolek'hule	C10H12O2
'Misa oa Molar	164.2
Botenya	1.0041 (khakanyo e fosahetseng)
Melting Point	50-52°C(lebone)
Boling Point	140°C10mm Hg(hote.)
Flash point	128.1°C
Solubility	Ha e kenelle ka metsing
Khatello ea Mouoane	8.98E-05mmHg ho 25°C
Ponahalo	Likristale tse se nang mebala, tsa prismatic (tse nchafalitsoeng ho tsoa ho anhydrous ethanol)
Mmala	Bosoeu
Merck	14,9390
pKa	7.06±0.30(E boletsoeng esale pele)
Boemo ba polokelo	E tiisitsoe ka ho omme, Mocheso oa Kamore
Botsitso	E tsitsitse selemo se le 1 ho tloha ka letsatsi la theko joalo ka ha ho fanoe. Tharollo ho DMSO kapa ethanol e ka bolokoa ho -20 ° ho fihlela likhoeli tse 4.
E hloahloa	Qoba ho kopana le oxides
Refractive Index	1.5190 (khakanyo)
MDL	MFCD00059582
Thuto ea in vitro	Liseleng tsa lisele tsa U87MG le T98G glioma, hinokitiol e bontša ho fokotseha ho itšetlehileng ka tekanyo ea ho sebetsa, ka litekanyetso tsa IC 50 tsa 316.5 ± 35.5 le 152.5 ± 25.3 µM, ka ho latellana. Hinokitiol e hatella ts'ebetso ea ALDH le bokhoni ba ho inchafatsa liseleng tsa stem tsa glioma, hape e thibela in vitro oncogenicity. Hinokitiol e boetse e fokotsa polelo ea Nrf2 ka lisele tsa stem tsa glioma ka mokhoa o itšetlehileng ka tekanyo. Hinokitiol (0-100 μM) e thibela kholo ea lisele tsa kankere ea colon ka mokhoa o itšetlehileng ka nako. Hinokitiol (5, 10 μM) e fokotsa DNMT1 le UHRF1 mRNA le polelo ea protheine, 'me e eketsa polelo ea TET1 ka ho ntlafatsa boemo ba 5hmC liseleng tsa HCT-116. Ho feta moo, hinokitiol e fokotsa boemo ba methylation mme e tsosolosa polelo ea mRNA ea MGMT, CHST10, le liphatsa tsa lefutso tsa BTG4.

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Matšoao a Kotsi	Xn - E Kotsi
Likhoutu tsa Kotsi	22 - E kotsi haeba e koetsoe
Tlhaloso ea Tšireletseho	36 - Apara liaparo tse loketseng tsa tšireletso.
WGK Jeremane	3
RTECS	GU4200000

Selelekela

Hinokiol, eo hape e tsejoang e le α-terpene alcohol kapa Thujanol, ke motsoako oa tlhaho oa tlhaho oo e leng oa e 'ngoe ea likarolo tsa turpentine. Hinoylol ke mokelikeli o se nang 'mala, o bonaletsang ka monko o monate oa phaene.

Hinokiol e na le lisebelisoa tse fapaneng. E sebelisoa haholo indastering ea litlolo le monko ho eketsa monko le monko ho lihlahisoa. Taba ea bobeli, tahi ea junipere e boetse e sebelisoa joalo ka sebolaea-khuru le sekoaelo, 'me hangata e sebelisoa ho lokiseng li-disinfectants le li-fungicides.

Ho na le mekhoa e 'maloa ea ho lokisa juniperol. Hangata, e ka ntšoa ka distillation ea oli e sa tsitsang ho tloha makhasi a junipere kapa limela tse ling tsa cypress, ebe e aroloa le ho hloekisoa ho fumana juniperol. Tahi ea Hinoki e ka boela ea etsoa ka motsoako oa lik'hemik'hale.

Lintlha tsa polokeho ea juniperol: Ha e na chefo e nyane mme hangata e nkuoa e bolokehile. Joalo ka motsoako oa lintho tse phelang, o ntse o hloka ho tšoaroa le ho bolokoa ka nepo. Qoba ho ama letlalo le mahlo, 'me u hlatsoe hang-hang ka metsi haeba u ka kopana ka phoso. E lokela ho bolokoa hole le malakabe a bulehileng le mocheso o phahameng, 'me e bolokoe sebakeng se phodileng, se omileng.

E fetileng: Z-ASP-OBZL(CAS# 4779-31-1)

E 'ngoe: 3-(Trifluoromethoxy) benzyl bromide (CAS# 50824-05-0)

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